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Cell Biology
Biomolecules
Enzymes
Nucleases
Endonucleases
Endonucleases
Endonucleases cleave DNA or RNA chains internally from the phosphodiester bonds connecting the nucleotides. Representing a broad class of nucleases, they are involved in many biological functions, such as DNA repair, homologous recombination, and viral integration. Commercially produced
Endonucleases
are available for specialized applications in DNA manipulation. For instance, T7
Endonuclease I
is used in recognition of short base deletions and insertions. AP Endonuclease creates single strand DNA breaks for DNA nicking.
Benzonase
, an engineered endonuclease, fully digests DNA and RNA down to 2 to 5 bases in length. For restriction endonucleases, see the
“Restriction Enzyme”
section in the enzyme search tool.
Endonucleases
Endonuclease I
Endonuclease III
Endonuclease IV
Endonuclease V
Endonuclease VIII
Benzonase
Editorial Articles
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Reviews
Cas9 Nuclease by IDT
I am performing CRISPR-Cas9 experiment on B cells and HEK cells. I am using Cas9...
Removal Of Contaminating Nucleic Acids ...
I have used Merckmillipore Benzonase nuclease to remove DNA and RNA from ...
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Endonucleases
Endonuclease I
Endonuclease III
Endonuclease IV
Endonuclease V
Endonuclease VIII
Benzonase