Molecular Characterization of Metastatic Prostate Cancer

USC Keck School of Medicine & Norris Comprehensive Cancer Center
Assistant Professor Translational Genomics
Dr. Manojlovic in an Assistant Professor in the department of Translational Genomics and the Director of the newly formed Keck Genomics Platform (KGP) at the Keck School of Medicine of University of Southern California. In 2017, with support of Keck Medicine led the creation of the state-of-the-art next generation sequencing center with emphasis on multi-disciplinary collaborative projects. KGP is a service platform designed to support Keck School of Medicine, greater USC, and its affiliates with a complete, high throughput next generation sequencing ecosystem that can support projects at all stages of development. KGP provides support in high quality sample processing, library constructions, and high throughput next generation sequencing of RNA, whole genome, exome, bi-sulfide, methylome, esoteric, and custom targeted assays by utilizing the Illumina platform such as MiSeq and NovaSeq. KGP also leverages high performance computational resources with in-house built pipelines and information management systems vital for a complete research-based precision medicine platform. KGP’s major mission is to build a collaborative environment and provide team-driven research support within the scope of the next generation technologies to ultimately drive advances in translational genomics and pave a way towards personalized medicine.

Prostate cancer is the most frequent malignancy in men in the United States with a 5-year survival rate for metastatic disease of 30%. Survival is influenced by the location of the metastases. Patients with prostate cancer that remains in the prostate and lymph nodes have a higher survival rate than those that experience distant metastasis. The aim of the research presented here is to develop predictive markers of metastatic prostate disease.Expand to see more

January 06, 2020

USC Keck School of Medicine & Norris Comprehensive Cancer Center
Assistant Professor Translational Genomics
Dr. Manojlovic in an Assistant Professor in the department of Translational Genomics and the Director of the newly formed Keck Genomics Platform (KGP) at the Keck School of Medicine of University of Southern California. In 2017, with support of Keck Medicine led the creation of the state-of-the-art next generation sequencing center with emphasis on multi-disciplinary collaborative projects. KGP is a service platform designed to support Keck School of Medicine, greater USC, and its affiliates with a complete, high throughput next generation sequencing ecosystem that can support projects at all stages of development. KGP provides support in high quality sample processing, library constructions, and high throughput next generation sequencing of RNA, whole genome, exome, bi-sulfide, methylome, esoteric, and custom targeted assays by utilizing the Illumina platform such as MiSeq and NovaSeq. KGP also leverages high performance computational resources with in-house built pipelines and information management systems vital for a complete research-based precision medicine platform. KGP’s major mission is to build a collaborative environment and provide team-driven research support within the scope of the next generation technologies to ultimately drive advances in translational genomics and pave a way towards personalized medicine.