Spatial Biology Platforms

The ability to observe cellular processes and phenotypes in terms of spatial and morphological context is valuable in many research areas, from basic research to clinical development in areas like immuno-oncology, neurology, cardiovascular and infectious diseases. Novel platforms allow researchers to bridge the gap between high-resolution tissue imaging and gene expression through RNA or protein detection. Methods can vary from multiplexed immunodetection of multiple protein biomarkers to whole transcriptome analysis of single tissue sections. Generally, both fresh frozen and FFPE tissue sample formats can be accommodated. Other notable features include rapid, automated imaging and integrated analysis software. Browse the spatial biology platforms below to determine which best suits the needs or capabilities of your project.

Spatial Biology Platforms

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Sponsored Products

PhenoCycler&#174;-Fusion 2.0
Akoya Biosciences
  • Description:
    Powered by high-speed imaging and proprietary barcoding technology, PhenoCycler®-Fusion 2.0 introduces multi-slide ...
  • Method:
    Inquire
CellScape&#8482; ChipCytometry&#8482; Instrument
Canopy Biosciences
  • Description:
    CellScape™ is the next generation in ChipCytometry™ instrumentation, advancing the cutting-edge platform for ...
  • Method:
    Highly multiplexed immunofluorescence of multiple protein ...
  • Scale:
    Whole tissue, single-cell, subcellular
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Cell DIVE Multiplexed Imager
Leica Microsystems
  • Description:
    Designed to give users the freedom and confidence to choose exactly how to design and execute their multiplexing ...
  • Method:
    Multiplex immunofluorescence imaging of 60+ biomarkers
  • Scale:
    Whole tissue, single cell
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COMET &trade;
Lunaphore Technologies SA
  • Description:
    COMET™ is a high-throughput, fully automated hyperplex platform, designed to obtain scalability and reproducibility ...
  • Method:
    Sequential immunofluorescence (SeqIF™); Runs of 40-plex
  • Scale:
    Whole tissue
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Citations:
(19)
MACSima&#8482; Platform
Miltenyi Biotec
  • Description:
    The revolutionary MACSima™ Platform streamlines your spatial biology research from end to end, reducing experimental ...
  • Method:
    Inquire
Citations:
(19)
Figures:
(1)
TissueFAXS Spectra Multispectral Tissue Cytometer
TissueGnostics
  • Description:
    Use TissueFAXS Spectra for whole-slide multispectral imaging as well as high-end image analysis. This system allows the ...
  • Method:
    Inquire
Citations:
(11)
The MERSCOPE Platform
Vizgen
  • Description:
    The MERSCOPE Platform is the first high plex, in situ single-cell spatial genomics solution. MERSCOPE uses MERFISH ...
  • Method:
    Multiplexed error-robust FISH (MERFISH) with automated image...
  • Scale:
    Whole tissue, single-cell, subcellular
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Citations:
(1)
Xenium Analyzer High-throughput in situ Analyzer
10x Genomics
  • Description:
    Xenium In Situ is the next-level in situ solution for subcellular profiling of 100s of RNA targets, in fresh frozen or ...
  • Method:
    Inquire
  • Scale:
    Whole tissue, single-cell, subcellular
RNAscope&#8482; In Situ Hybridization
Advanced Cell Diagnostics
  • Description:
    RNAscope Technology is a novel in situ hybridization (ISH) assay for detection of target RNA within intact cells. The ...
  • Method:
    In situ hybridization (ISH) assay - single to 12-plex
  • Scale:
    Whole tissue, single cell
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PhenoCycler&trade; instrument
Akoya Biosciences
  • Description:
    The PhenoCycler™ instrument (formerly CODEX®) is a cutting-edge fluidics control unit that integrates with the...
  • Method:
    Automated cycling and labeling of analytes for whole-slide ...
  • Scale:
    Whole tissue, single cell
Read More
Citations:
(30)
Figures:
(2)
PhenoCycler-Fusion System
Akoya Biosciences
  • Description:
    The PhenoCycler™-Fusion system is the fastest spatial biology solution that enables ultrahigh-plex spatial ...
  • Method:
    Automated cycling and iterative imaging of 100+ biomarkers ...
  • Scale:
    Whole tissue, single cell
Read More
Citations:
(4)
Figures:
(2)
CosMx&#8482; Spatial Molecular Imager
NanoString Technologies
  • Description:
    CosMx SMI is the first high-plex in situ analysis platform to provide spatial multiomics with formalin-fixed paraffin-...
  • Method:
    Multiplexed, cyclic FISH; 1000-plex for RNA and 100-plex for...
  • Scale:
    Whole tissue, single-cell, subcellular
Read More
Citations:
(59)
Figures:
(1)
GeoMx&#8482; Digital Spatial Profiler
NanoString Technologies
  • Description:
    Using the GeoMx DSP workflow, whole tissue sections can be imaged and stained for RNA or protein. Researchers can then ...
  • Method:
    Stain and image tissue slides using DSP barcoded antibodies ...
  • Scale:
    Whole tissue
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iMScope QT Imaging Mass Microscope
Shimadzu
  • Description:
    The iMScope QT Imaging Mass Microscope is a combination of an optical microscope and an AP-MALDI ion source enabling ...
  • Method:
    Inquire
Citations:
(8)
G4X Spatial Sequencer
Singular Genomics
  • Description:
    High-throughput in-situ spatial sequencing for transcriptomic and proteomic analysis from FFPE samples at subcellular ...
  • Method:
    Inquire
  • Scale:
    Whole tissue, single cell
Hyperion+&#8482; Imaging System
Standard BioTools Inc.
  • Description:
    The Hyperion+™ Imaging System uses Imaging Mass Cytometry™ (IMC™) to visualize the complex spatial biology of the ...
  • Method:
    Imaging mass cytometry (CyTOF) using mass-tagged antibodies;...
  • Scale:
    Whole tissue, single cell
Read More
Citations:
(24)
Figures:
(1)
Visium Spatial Gene Expression
10x Genomics
  • Description:
    Visium Spatial Gene Expression is a next-generation molecular profiling solution for classifying tissue based on total ...
  • Method:
    Slide-based mRNA capture and sequencing to analyze the whole...
  • Scale:
    Whole tissue, single cell
Read More
Select up to 5 products from above to compare or request more information.

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Miltenyi Biotec
MACSima
1
1 Figure from 19 Publications
Akoya Biosciences
PhenoCycler
6
2 Figures from 30 Publications
Akoya Biosciences
PhenoCycler-Fusion
1
2 Figures from 4 Publications
NanoString Technologies
CosMx
3
1 Figure from 59 Publications
Standard BioTools Inc.
Hyperion+
7
1 Figure from 24 Publications
Showing 5 of 5 products
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  • 10x Genomics
  • Advanced Cell Diagnostics
  • Akoya Biosciences
  • Canopy Biosciences
  • Leica Microsystems
  • Lunaphore Technologies SA
  • Miltenyi Biotec
  • NanoString Technologies
  • Shimadzu
  • Singular Genomics
  • Standard BioTools Inc.
  • TissueGnostics
  • Vizgen